Document Type : Original Article


1 Department of Medical‑Surgical Nursing, Nursing and Midwifery Care Research Center, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran

2 Department of Gastroenterology and Hepatology, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran

3 Department of Health Sciences, Social Determinants of Health Research Center, Mashhad University of Medical Sciences, Mashhad, Iran


Inflammatory bowel disease (IBD), including Crohn’s and ulcerative colitis diseases, is characterized
by clinical periods of remission and relapse. Excessive care stress can have long‑term negative
physical and psychological consequences not only for caregivers but also for the recipients of care.
This integrative review aims to identify, describe, and synthesize the results of current available
research focused on the burdens of IBDs on family caregiver. An integrative review was performed
using Whittemore and Knafl methodology. A systematic search of electronic databases including
Web of Science, PubMed, Embase, and Scopus from January 2000 to October 2019 was conducted.
Articles were included if published in English and focus on IBD burden on family caregivers. Of 730
records, 16 articles with quantitative, qualitative, and Q methodology study designs were eventually
included in the review. The synthesis of these articles led to the identification of four key types of
effects: biopsychosocial, daily life activities, physical health, and financial. The chronic and relapsing
nature of IBD exposes family caregivers to considerable risk. Thus, the care burden of IBD patients’
caregivers needs to be evaluated continuously and relieved through family‑centered interventions.


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