Journal of Education and Health Promotion

Evaluation of nutritional adjustment program on quality of life in children with chronic liver disease

Document Type : Original Article

Authors

. Seyed Ali Jafari
. Aramesh Rezaeian 1
. Zahra Namjou 2
. Majid Ghayour-Mobarhan 3
. Zahra ghaneifar 4

1 Evidence Based Care Research Center, Instructor Pediatric Nursing, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran Department of Pediatrics, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran

2 MSc in Pediatric Nursing, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran, Department of Pediatrics, School of Nursing and Midwifery, Shahid Sadoughi University of Medical Sciences, Yazd, Iran,

3 Metabolic Syndrome Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran, International UNESCO Center for Health Related Basic Sciences and Human Nutrition, Department of Nutrition, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

4 Graduate of Nutrition, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Abstract
BACKGROUND: Chronic liver disease is associated with decreased quality of life. The quality of life
of children with chronic liver disease is related to their quality of life. Malnutrition is associated with
death from cirrhosis, development of complications, and health‑related quality of life in people with
liver disease. Therefore, this study was conducted to determine the effect of nutritional adjustment
program on quality of life in children with chronic liver disease.
MATERIALS AND METHODS: This clinical trial study was performed on children with chronic liver
disease referred to the nutrition clinic of Ghaem Educational‑Research Center in Mashhad in 2015.
In this study, 77 children with chronic liver disease were randomly divided into two groups. Before
and after the intervention, patients’ quality of life was assessed with the PedsQL™ 4.0 generic core
scale questionnaire. Data analysis was performed using SPSS16 software.
RESULTS: In the postintervention stage, the mean total score of quality of life in the experimental
group was 1965.0 ± 270.9 and in the control group was 1522.5 ± 321.3 (P < 0.001). The difference
in quality of life score of physical, social, and school performance in the two groups was significant.
CONCLUSION: According to the results of this study, it seems that interventions that can improve
the quality of life of children with chronic liver disease can be an important step in advancing these
people toward a healthy and quality life. As a result, it is possible to take steps to improve the quality
of life of patients by encouraging children with liver disease and providing information about diet.

Keywords

Child
chronic liver disease
nutrition
quality of life
1. Sischo L, Broder HL. Oral health‑related quality of life: What,
why, how, and future implications. J Dent Res. 2011 Nov;
90(11):1264‑70. doi: 10.1177/0022034511399918. Epub 2011 Mar
21. PMID: 21422477; PMCID: PMC3318061.
2. Bonomi AE, Patrick DL, Bushnell DM, Martin M. Validation of the
United States’ version of the World Health Organization Quality
of Life (WHOQOL) instrument. J Clin Epidemiol 2000;53:1‑2.
3. King CR, Hinds PS. Quality of Life: From Nursing and Patient
Perspectives. Amazon Jones & Bartlett Publishers; 2011.
4. Cynthia R, Pamela S. Quality of life from nursing and patient
perspectives: Theory practice. Canada: Jones and Bartllet; 1999.
5. Partovi S, Kianifar HR, Gholami Robatsangi M, Ghorbani Z,
SaeidiR. Evaluation of massage with oil containing medium chain
triglyceride on weight gaining in preterm. Koomesh 2009;11:1‑6.
6. Saeidi R, Ziadi Lotf Abadi M, Saeidi A, Gholami Robatsangi M.
The effectiveness of mother infant interaction on infantile colic.
Iran J Neonatol 2014;4:37‑8.
7. Finkelstein FO, Wuerth D, Finkelstein SH. Health related quality
of life and the CKD patient: Challenges for the nephrology
community. Kidney Int 2009;76:946‑52.
8. WHO. Innovative care for chronic conditions: Building blocks for
actions: Global report; 2002.
9. Zandi M, Adib‑Hajbagheri M, Memarian R, Nejhad AK,
Alavian SM. Effects of a self‑care program on quality of life of
cirrhotic patients referring to Tehran Hepatitis Center. Health
Qual Life Outcomes 2005;3:35.
10. Safizadeh HG, Afsharpoor S. Quality of life in hemodialysis
patients. Payesh Q 1384;1:29‑35.
11. Zarei AR, Jahanpour F, Alhani F, Razazan N, Ostovar A. The
Impact of multimedia education on knowledge and self‑efficacy
among parents of children with asthma: A randomized clinical
trial. J Caring Sci 2014;3:185‑92.
12. Marcdante K, Kliegman RM, Behrman RE, Jenson HB. Nelson
Essentials of Paediatrics. Elsevier Elsevier Health Sciences; 2010.
13. McMahon BJ. Epidemiology and natural history of hepatitis B.
Semin Liver Dis. 2005;25 Suppl 1:3‑8. doi: 10.1055/s‑2005‑915644.
PMID: 16103976.
14. Borgaonkar MR, Irvine EJ. Quality of life measurement in
gastrointestinal and liver disorders. Gut 2000;47:444‑54.
15. Marchesini G, Bianchi G, Amodio P, Salerno F, Merli M, Panella C,
et al. Factors associated with poor health‑related quality of life of
patients with cirrhosis. Gastroenterology 2001;120:170‑8.
16. Gulati R, Radhakrishnan KR, Hupertz V, Wyllie R, Alkhouri N,
Worley S, et al. Health‑related quality of life in children withautoimmune liver disease. J Pediatr Gastroenterol Nutr
2013;57:444‑50.
17. Kamath BM, Chen Z, Romero R, Fredericks EM, Alonso EM,
Arnon R, et al. Quality of Life and Its Determinants in a
Multicenter Cohort of Children with Alagille Syndrome. J Pediatr
2015;167:390‑6000.
18. Gezer C. Impact of Dietary Pattern on Human Life Quality and
Life Expectancy: A Mini‑Review. Research & Investigations in
Sports Medicine. 2018;2(5):1‑4.
19. Ooi PH, Gilmour SM, Yap J, Mager DR. Effects of branched chain
amino acid supplementation on patient care outcomes in adults
and children with liver cirrhosis: A systematic review. Clin Nutr
ESPEN 2018;28:41‑51.
20. Nightingale S, Ng VL. Optimizing nutritional management
in children with chronic liver disease. Pediatr Clin North Am
2009;56:1161‑83.
21. Yarmohammadi N, Rassafiani M, Joveini G, Rostami HR,
Biglarian A, Behnia F. Validity and reliability of the Persian
version of parent report of the quality of life questionnaire for
adolescence with cerebral palsy. J Mod Rehabil 2016;9:111‑9.
22. Parmar A, Vandriel SM, Ng VL. Health-related quality of life
after pediatric liver transplantation: A systematic review. Liver
Transplant 2017;23:361‑74.
23. Tehranian S, Jafari S, Yousofi J, Kiani M, Seyedin S, Khakshour A,
et al. Health‑related quality of life (HRQOL) in children with
chronic liver disease in North East Iran using PedsQL™ 4.0.
Electron Physician 2015;7:1214.
24. Nel ED, Terblanche AJ. Nutritional support of children with
chronic liver disease. S Afr Med J 2015;105:607.
25. Sobhonslidsuk A, Silpakit C, Kongsakon R, Satitpornkul P,
Sripetch C, Khanthavit A. Factors influencing health‑related
quality of life in chronic liver disease. World J Gastroenterol
2006;12:7786‑91.
26. Chang MY, Velez FG, Demer JL, Isenberg SJ, Coleman AL,
Pineles SL. Quality of life in adults with strabismus. Am J
Ophthalmol 2015;159:539‑4400.
27. Zandi M, Alavian S, Memarian R, Kazem Nejad A. Assessment
of the effect of self care program on quality of life in patients with
cirrhosis referred to Tehran hepatitis center in 2003. Razi J Med
Sci 2004;11:411‑20.
28. Campbell KL, Ash S, Bauer JD. The impact of nutrition
intervention on quality of life in pre‑dialysis chronic kidney
disease patients. Clin Nutr 2008;27:537‑44.
29. Aghakhani N, Samadzadeh S, Mafi TM, Rahbar N. The impact
of education on nutrition on the quality of life in patients on
hemodialysis: A comparative study from teaching hospitals. Saudi
J Kidney Dis Transpl 2012;23:26‑30.
30. Nguyen HT, Collins PF, Pavey TG, Nguyen NV, Pham TD,
Gallegos DL. Nutritional status, dietary intake, and health‑related
quality of life in outpatients with COPD. Int J Chron Obstruct
Pulmon Dis 2019;14:215‑26.
31. Capra S, Ferguson M, Ried K. Cancer: Impact of nutrition
intervention outcome‑nutrition issues for patients. Nutrition
2001;17:769‑72.
32. Lindqvist C, Slinde F, Majeed A, Wahlin S. Nutrition impact
symptoms affects quality of life and nutritional status in patients
with chronic liver disease. Clin Nutr 2018;37:S64‑5.
33. Tol A, Sharifirad G, Eslami A, Shojaeizadeh D, Alhani F,
Tehrani MM. Analysis of some predictive factors of quality of life
among type 2 diabetic patients. J Educ Health Promot 2015;4:9.
34. Kiani‑Sheikhabadi M, Beigi M, Mohebbi‑Dehnavi Z. The
relationship between perfectionism and body image with eating
disorder in pregnancy. J Educ Health Promot 2019;8:242.
35. Noroozi M, Gholami M, Mohebbi‑Dehnavi Z. The relationship
between hope and resilience with promoting maternal attachment
to the fetus during pregnancy. J Edu Health Promot 2020;9:54.
Journal of Education and Health Promotion
Volume 11, Issue 4
May 2021
Pages 1-7

Home

Guide for Authors

Submit Manuscript

Reviewers

Contact Us