Document Type : Original Article
Authors
- . Rahmatollah Moradzadeh
- . Seyed Mohammad Jamalian 1
- . Javad Nazari 2
- . Alireza Kamali 3
- . Bahman Sadeghi 4
- . Zahra Hosseinkhani 5
- . Masoomeh Sofian 6
- . Maryam Zamanian
1 Department of Forensic Medicine and Poisoning, Arak University of Medical Sciences, Arak, Iran
2 Department of Pediatrics, School of Medicine, Arak University of Medical Sciences, Arak, Iran
3 Department of Anesthesiology and Critical Care, Arak University of Medical Sciences, Arak, Iran
4 Department of Social Medicine, School of Medicine, Arak University of Medical Sciences, Arak, Iran
5 Metabolic Diseases Research Center, Research Institute for Prevention of Non-Communicable Diseases, Qazvin University of Medical Sciences, Qazvin, Iran
6 Infectious Disease Research Center, Arak University of Medical Sciences, Arak, Iran
Abstract
BACKGROUND: To have a thorough understanding of epidemic surveillance, it is essential to broaden
our knowledge of death tolls worldwide. This study aimed to determine the age‑standardized mortality
rate (ASMR) and predictors of mortality among coronavirus disease 2019 (COVID‑19) patients.
MATERIALS AND METHODS: In this cross‑sectional design, all COVID‑19 patients with a
positive polymerase chain reaction test in the population covered by Arak University of Medical
Sciences (AUMS) were entered to the study. Data collection was conducted by phone interview.
The study variables comprised age, sex, coronary heart diseases, diabetes, and some symptoms
at admission. The adjusted odds ratio (OR) and 95% confidence intervals (CIs) were obtained by
logistic regression. The direct method was applied to calculate ASMR (per 100,000) of COVID‑19.
The analysis was applied by STATA software 12.0.
RESULTS: A total of 208 cases of COVID‑19 (out of 3050 total infected cases) were dead and
2500 cases were recovered. The mean age of dead patients was 70 years. The COVID‑19 fatality
rate in the population equaled 6.8%; in those patients who were 70 years old or more, however, the
case fatality rate was 16.4%. The ASMR of COVID‑19 was 12.9 (CI 95%: 11.2, 14.8). The odds of
COVID‑19‑related death in the age over 60 were 10.87 (CI 95%: 6.30, 18.75) times than lower 45 years
old. Moreover, it was observed that COVID‑19 significantly increased the odds of COVID‑19‑related
death in diabetes patients (OR = 1.45, CI 95%: 1.02, 2.06, P = 0.036).
CONCLUSION: The ASMR of COVID‑19 was relatively higher in males than females. In general, the
COVID‑19 fatality rate was relatively high. We found that older age and diabetes can have impact
on the death of COVID‑19, but the headache was found to have a negative association with the
COVID‑19‑related death.
Keywords
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