Document Type : Original Article


1 School of Medicine, Tehran University of Medical Sciences, Tehran, Iran

2 Department of Epidemiology and Biostatistics, School of Public Health,


Introduction: Since pemphigus vulgaris (PV) is a chronic disease and regarding its autoimmune
nature, patients need to adopt self‑care behaviors. This study aimed to assess the impacts of
an educational program based on health belief model (HBM) on adopting self‑care behaviors
among patients with PV referred to Razi Hospital. Materials and Methods: Eighty‑eight patients
with PV were randomized in an educational intervention study in two groups in 2013–2014. The
intervention group attended a 6 months self‑care educational program in a specialized outpatient
clinic, in addition to the regular care presented for both groups. To collect information about
demographic characteristics, PV‑related variables, and HBM constructs items, a self‑designed
questionnaire was used. Data were analyzed by SPSS 20. A P < 0.05 was considered as
statistically significant. Results: Increase in perceived susceptibility, severity, and benefits score
were significantly higher in intervention group compared with controls when adjusting for the
difference in baseline scores of these HBM constructs and house ownership and employment
status distribution in two groups using ANCOVA (P < 0.001). Furthermore, after intervention,
the decrease in perceived barriers’ scores was significantly more than controls (P < 0.001),
However, the decrease in cues to action score was not found significant (P = 0.380).
Discussion: The results of this study show the effects of an HBM‑based educational program
as a tertiary preventive measure on adopting self‑care behaviors in patients that can help
them achieve self‑efficacy in controlling their disease and enhancing their treatment process.


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