Journal of Education and Health Promotion

Chemotherapy administration checklist for patients receiving chemotherapy: Development and validation

Authors

. Gitika Miglani
. Ashok Kumar
. Vandna Pandey
. Puneet Pareek
. Shrikant K. Nair

Department of Radiation Oncology, AIIMS, Jodhpur, Rajasthan, India

Abstract
BACKGROUND: With the increase in the number of new cancer cases, the number of patients
receiving chemotherapy increases. The administration of chemotherapy is a very significant task.
Unfortunately, the availability of a chemotherapy administration checklist still lags behind. The aim
is to develop a chemotherapy administration checklist for patients receiving chemotherapy.
MATERIALS AND METHODS: This study was conducted at the oncology day care and in‑patient
department (IPD) wards of the All India Institute of Medical Sciences, Jodhpur, Rajasthan.
Methodological research design was used in this study. It took place in five phases: preliminary phase
includes literature review, focussed group discussion, assessment of current practices, generation
of item pool, and preparation of preliminary draft; then its validation by modified Delphi technique,
pilot testing; final try out, and evaluation phase. A total of 260 patients were enrolled.
RESULTS: The content validity index was 0.97. To perform factor analysis and principal component
analysis KMO and Bartlett’s test of sphericity was used, which allows the data for factor analysis to
yield eight components. A total of 26 items were formulated. The scoring was done dichotomously;
a score of 1 is for done and 0 for not done and not applicable. Cronbach’s alpha was used to find
out the internal consistency of the checklist was found to be 0.72. For interrater reliability, the Cohen
kappa’s value was found to be 0.91.
CONCLUSIONS: Chemotherapy administration checklist was a valid and reliable checklist. This
checklist is feasible and easy to incorporate into clinical practices.

Keywords

Cancer
checklist
chemotherapy
construct validity
modified Delphi technique
1. World Health Organization. International Agency for Research on
Cancer. Latest Global Cancer Data 2020. Available from: https://
www.iarc.who.int.
2. Kreidieh FY, Moukadem HA, Saghir NS. Overview, prevention
and management of chemotherapy extravasation. World J Clin
Oncol 2016;7:87‑97.
3. Amjad MT, Chidharla A, Kasi A. Cancer Chemotherapy.
StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing;
2022 Jan. Available from: https://www.ncbi.nlm.nih.gov/books/
NBK564367/.
4. PengQ, WuW. Development and validation of oral chemotherapy
self‑management scale. BMC Cancer 2020. doi: 10.1186/
s12885‑020‑07404‑0.
5. Grunigen SV, Geissbuhlar A, Bonnabry P. Cyto‑SAT:
A self‑assessment tool for the safe handling of cytotoxic drugs
adapted for use in low‑ and middle‑income countries. J Oncol
Pharm Pract 2021;27:1422‑31.
6. Tofthagen CS, McMillan SC, Kip KE. Development and
psychometric evaluation of the chemotherapy‑induced
peripheral neuropathy assessment tool. Cancer Nurs
2011;34:E10‑20.
7. Kim SH, Park JH. Develop and validate nutrition screening tool for
hospitalized cancer patients. J Korean Acad Nurs 2012;42:632‑43.
8. Kano T, Kanda K. Development and validation of a
chemotherapy‑induced taste alteration scale. Oncol Nurs Forum
2013;40:E79‑85.
9. Jeyaram S, Veeraiah S, Elangovan V. Validation of the symbolic
assessment of fatigue extent (SAFE)‑a cancer fatigue tool with
visual response formats. Support Care Cancer 2017;25:1111‑9.
10. Maguire R, Kotronoulas G, Donnan PT, Paterson C, McCann L,
Connaghan J, et al. Development and preliminary testing of a brief
clinical tool to enable daily monitoring of chemotherapy toxicity:
The daily chemotherapy toxicity self‑ assessment questionnaire.
Eur J Cancer Care 2018;27:e12890.
11. Kanda K, Fujimoto K, Mochizuki R, Ishida K, Lee B. Development
and validation of the comprehensive assessment scale for
chemotherapy‑induced peripheral neuropathy in survivors of
cancer. BMC Cancer 2019;19:904.
Journal of Education and Health Promotion
Volume 12, Issue 11
December 2022
Pages 1-6

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