Document Type : Original Article
Authors
1 Department of Community Health Nursing, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2 Student Research Committee, Department of Operating Room Nursing, School of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, Iran
3 Nursing Care Research Center, School of Nursing and Midwifery, Iran University of Medical Science, Tehran, Iran
Abstract
Recent studies have reported inconclusive results regarding the therapeutic effects of Rosa
damascena on the outcomes of primary dysmenorrhea (PD) and premenstrual syndrome (PMS).
Hence, this study is aimed to summarize the findings of randomized controlled trials (RCTs)
regarding the effects of this treatment on menstruation‑related pain as the primary outcome and
menstruation‑related headache, fatigue, anxiety, and bloating as the secondary outcomes. This
study evaluated parallel‑group and cross‑over RCTs on aromatherapy, topical treatment, or
oral intake of R. damascena products for the treatment groups versus placebo, nontreated, or
conventional treatment groups. Seven electronic databases (Web of Science Core Collection,
Scopus, Embase, CENTRAL, CINAHL, SID, and MagIran) and one search engine (PubMed) were
searched from inception to January 15, 2021. Of 1468 trials found in the initial search, 983 potentially
relevant articles were screened by title and abstract. After examining the full‑text of 13 studies for
compliance with the inclusion criteria, seven studies were considered eligible for this review. A
random‑effects model was used to pool the data; otherwise, a narrative summary was presented.
The retrieved studies were conducted on females with PD or PMS, aged 18–35 years. The total
sample size of the intervention and comparator arms was 276 and 272. The results showed that
R. damascena had a nonsignificant alleviating effect on the menstruation‑related pain (weighted
mean difference [WMD]: −0.47; 95% confidence interval [CI]: −1.25, 0.31; P = 0.234). Such findings
were also found for menstruation‑related anxiety (WMD: −0.40; 95% CI: −0.91, 0.11; P = 0.125).
However, the treatment significantly reduced the menstruation‑related headache (WMD: −0.42;
95% CI: −0.74, −0.11; P = 0.008), fatigue (WMD: −0.48; 95% CI: −0.87, −0.09; P = 0.015), and
bloating (WMD: −0.72; 95% CI: −1.21, −0.22; P = 0.005). Since R. damascena had no significant
effects on menstruation‑related pain and anxiety, further studies with improved methodological
quality are suggested to evaluate the effects of the treatment on these symptoms, using different
dosages and durations.
Keywords
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