Document Type : Original Article


1 Women Health Research Centre, School of Nursing and Midwifery, Isfahan University of Medical Sciences

2 Behavioral Sciences Research Center, Isfahan University of Medical Sciences

3 Nursing and Midwifery Care Research Center, School of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran


BACKGROUND AND AIM: Prenatal mental health has been shown to be related with postpartum
depression. However, the role of mental and psychological factors in postpartum depression requires
especial attention. Furthermore, the relationship between demographic factors and postpartum
depression is contradictory. The study was aimed to identify role of prenatal anxiety and depression
and demographic factors with postpartum depression.
MATERIALS AND METHODS: A prospective cohort study was conducted with 303 pregnant women
who have gestational age from 28 to 36 weeks and referred to health‑care centers in Isfahan city
and follow‑up for 6–12 weeks after postpartum. Data were collected using the demographic form,
Edinburgh depression, and anxiety Spielberger questionnaire during pregnancy and Edinburgh
depression inventory in the 6th and 12th weeks after childbirth. Descriptive statistics and linear logistic
regression were used to analyze the data. In demographic factors, data were analyzed using the
Student’s t‑test, Chi‑square, Pearson and Spearman test and after the meaningfulness of regression
was used.
RESULTS: Results showed that the 6 and 12 weeks after childbirth, 61 patients (20/1%) and
33 patients (10/9%) had postpartum depression. The most important risk factors for depression
in the first 6 weeks were history of infertility (confidence interval [CI]: 0.56–0.767) (P = 0.018) and
history of depression (CI: 1.155–1.369) (P = 0.000) and in 12 weeks, postpartum were history of
depression (CI: 0.072–1.305) (P = 0.001).
CONCLUSION: Infertility and history of depression during pregnancy were two risk factors of
postpartum depression which should be taken into consideration during prenatal care.


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