Document Type : Original Article


1 Department of Nursing, Tehran University of Medical Sciences, Tehran,

2 Department of Medicine, School of Medicine, Isfahan University of Medical Sciences,

3 Department of Adult Health Nursing, School of Nursing and Midwifery, Behavioral Sciences Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.

4 Department of Adult Health Nursing, School of Nursing and Midwifery

5 Department of Nursing, School of Medical Sciences, Tarbiat Modares University, Tehran


Introduction: Nausea is the worst and most prevalent chemotherapy‑induced complication
experienced by 70–80% of patients despite mediation therapy. Reduction of nausea is one of
the most important roles of oncologist nurses. Today, complementary therapies in addition
to classic medicine, because of their lower costs, receive much attention. Nonetheless, their
safety and effectiveness are not yet proven. The purpose of this research was to investigate the
effect of therapeutic touch plan as a complementary therapy on acute nausea in women with
breast cancer in 2012–2013 in Isfahan, Iran. Materials and Methods: A quasi‑experimental,
single‑blind, randomized control trial with three groups (control, placebo and intervention) was
performed at the Isfahan Seyedolshohada (AS) Teaching Hospital, Isfahan, in 2012–2013. The
intervention was therapeutic touch plan on women with breast cancer, with the three groups
receiving the same medicine regimen. Information was recorded by a checklist after infusion of
chemotherapy drugs. Data analysis was performed by SPSS, ANOVA and Kruskal–Wallis tests.
Results: The ANOVA test showed that the therapeutic touch plan was significantly effective in
reducing the duration of nausea compared with the control and placebo groups (P < 0.001).
The Kruskal–Wallis test showed that the frequency of occurrence of nausea was also reduced
in the intervention and placebo groups compared with the control group (P < 0.001). The
therapeutic touch plan was significantly effective in delaying the onset of nausea compared
with the control and placebo groups (P < 0.001). Conclusion: This research showed that the
therapeutic touch plan is effective in reducing acute chemotherapy‑induced nausea; thus,
education and implementation of the therapeutic touch plan is proposed for clinical nurses.


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