Journal of Education and Health Promotion

Assessing the presence of Chlamydia trachomatis genome in pregnant women with spontaneous abortion using polymerase chain reaction method in Yasuj: First report from Southwest of Iran

Authors

. Alborz Jahangiri Sisakht 1
. Navid Omidifar 2
. Nahid Mohamadkhani 1
. Maryam Karimpoorfard 3
. Mohammad Kargar 4
. Mansoureh Shokripour 5

1 Department of Medical Microbiology, Paraclinic Faculty, Yasuj University of Medical Sciences, Yasuj,

2 Department of Pathology, School of Medicine, Shiraz University of Medical Sciences, Clinical Education Research Center, Shiraz University of Medical Sciences, Shiraz

3 Department of Research and Development, Dena Clinical Laboratory, Private Sector, Yasuj

4 Department of Microbiology, Azad University, Branch Jahrom, Jahrom, Iran

5 Department of Pathology, School of Medicine, Shiraz University of Medical Sciences

Abstract
Abstract:
CONTEXT: Chlamydia trachomatis is one of the most prevalent factors of sexually transmitted
diseases worldwide, which causes abortion, premature rupture of membrane, uterine cervicitis, pelvic
inflammatory diseases, and ectopic pregnancy.
AIMS: The aim of this study was to investigate the presence of C. trachomatis genome in pregnant
women with abortion in Yasuj, Iran.
SETTINGS AND DESIGN: This is a descriptive–analytical study in Shahid Mofateh Gyneco‑obstetrics
clinic and Emam sajjad Hospital.
SUBJECTS AND METHODS: Specimens of cervix, urine, placenta, and blood of 107 pregnant
women were simultaneously collected at maternity ward and operation room and were stored for
molecular tests. The molecular tests were performed, and the results were analyzed.
STATISTICAL ANALYSIS USED: Analysis was performed using SPSS software 9.1 (IBM, Illinois,
Chicago, USA) with descriptive–analytical statistics.
RESULTS: Of 107 women, 15 had polymerase chain reaction‑positive tests for C. trachomatis. The age
of the studied individuals was 15–38 years with mean age of 26.6 years. The highest infection rates were
in the age group of 21–25 years (7.47%), and the lowest frequency was in the age group of 36–40 years.
A significant difference was noted between the number of first abortions in the case and control groups.
CONCLUSIONS: Our results showed that C. trachomatis as a sexually transmitted agent causes
severe complications such as abortion; thus, it is important to screen pregnant and sexually active
women who are craving to carry a baby.

Keywords

Abortion
Chlamydia trachomatis
pregnant women
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Journal of Education and Health Promotion
Volume 7, Issue 3
May and June 2017
Pages 1-5

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