Authors

Department of Nursing, Medical‑Surgical Group, Faculty of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran

Abstract

BACKGROUND: Elderly people often suffer from sleep disorders. Chamomile due to the many health
benefits such as sedation may be effective in improving sleep quality in elderly people. This study
aimed to determine the effect of Matricaria chamomilla extract on sleep quality in elderly people
admitted to nursing homes of Isfahan in 2014.
MATERIALS AND METHODS: The present study is a quasi‑experimental clinical trial. The study
population was 77 cases of elderly hospitalized in nursing homes. Participants were selected through
random continuous sampling and divided into intervention and control groups. The intervention group
received 400 mg oral capsules of chamomile twice daily, after lunch and after dinner for 4 weeks. The
control group did not receive the intervention. Sleep quality in older adults before and after intervention
were compared using the Pittsburgh Sleep Quality Index questionnaire. Data were analyzed using
descriptive statistics and paired t‑ and independent t‑tests, one‑way analysis of variance and liner
regression analysis, using SPSS software version 17.
RESULTS: Before intervention, the mean score of sleep quality both experimental and control groups
showed no significant difference (P > 0.05). After intervention, the mean score of sleep quality was
a significant difference between experimental and control groups (P < 0.001).
CONCLUSIONS: Oral administration of chamomile extract has sedative properties in sleep quality of
hospitalized elderly patients in nursing homes. Therefore, it can be used in similar cases and nursing care.

Keywords

1. Narang I, Manlhiot C, Davies‑Shaw J, Gibson D, Chahal N,
Stearne K, et al. Sleep disturbance and cardiovascular risk in
adolescents. CMAJ 2012;184:E913‑20.
2. Asadnia S, Sepehrianazar F, Mosarrezaii Aghdam A,
Saadatmand S. Comparison of sleep quality and migraine
headaches in people with proper and improper and poor sleep.
Urmia Med J 2013;23:799‑806.
3. Yaremchuk K, Roehrs T. Does perioperative sleep disruption
impact pain perception? Laryngoscope 2012;122:2613‑4.
4. Dijk DJ. Sensitive to sleep loss or not: Neurons, working memory,
insomnia and the heart. J Sleep Res 2013;22:237‑8.
5. Saydshohadai M, Heshmat SH, Seidfatemi N, Haghani H,
Mehrdad N. The spiritual health of seniors living in sanitarium
and home residents. IJN 2013;26:11‑20.
6. Cooke JR, Ancoli‑Israel S. Normal and abnormal sleep in the
elderly. Handb Clin Neurol 2011;98:653‑65.
7. Rejeh N, Heravi‑Karimooi M, Montazeri A, Foroughan M.
Psychometric properties of the Iranian version of the facts on
aging quiz (FAQI). Payesh 2012;11:245‑51.
8. Abbasi B, Kimiagar M, Shirazi M, Hedayati M, Sadeghniiat K,
Taheri P, et al. Effect of magnesium supplementation on calorie
intake and weight loss of overweight or obese insomniac elderlysubjects: A double‑blind randomized clinical trial. Iran J Nutr Sci
Food Technol 2012;7:31‑40.
9. KunzD, MahlbergR. Atwo‑part, double‑blind, placebo‑controlled
trial of exogenous melatonin in REM sleep behaviour disorder.
J Sleep Res 2010;19:591‑6.
10. Rudolph U, Knoflach F. Beyond classical benzodiazepines: Novel
therapeutic potential of GABAA receptor subtypes. Nat Rev Drug
Discov 2011;10:685‑97.
11. Makvandi S, Zargar Shoushtar S. Midwifery students’
attitudes towards herbal medicine and its application in
obstetric. Jentashapir Journal of Health Research (Jentashapir)
2012:81‑6.
12. Posadzki P, Watson LK, Alotaibi A, Ernst E. Prevalence of herbal
medicine use by UK patients/consumers: A systematic review of
surveys. Focus Altern Complement Ther 2013;18:19‑26.
13. Namvaran‑Abbas‑AbadA, Khayat‑NouriM. Interactions between
Matricaria recutita and Cisplatin on PTZ‑induced seizure threshold
in mice. KAUMS J (FEYZ) 2011;15:188‑93.
14. Afzali SF, Shariatmadari H, Hajabbasi MA. Sodium chloride
effects on seed germination, growth and ion concentration in
chamomile (Matricaria chamomilla). Iran Agric Res 2010;29:107‑18.
15. Ariamanesh F, Malekshahi F, Safari M. The effect of foot massage
on night sleep quality in hemodialysis patients. Quartely research
journal 2015;17:71‑7.
16. Iwasaki M, Hirose T, Mita T, Sato F, Ito C, Yamamoto R, et al.
Morningness – Eveningness questionnaire score correlates with
glycated hemoglobin in middle‑aged male workers with type 2
diabetes mellitus. J Diabetes Investig 2013;4:376‑81.
17. Ong JC, Cardé NB, Gross JJ, Manber R. A two‑dimensional
approach to assessing affective states in good and poor sleepers.
J Sleep Res 2011;20:606‑10.
18. Khani F, Samsam Shariat S, Atashpour S. A Study of the
relationship between personality traits with occupational
accidents and quality of sleep among road drivers in Isfahan
city (Year 1390). Secur Soc Order Strateg Stud J 2013;1:75‑88.
19. Malek M, Halvani G, Fallah H, Jafari Nodoushan R. A study of the
relationship between the Pittsburgh sleep quality index and road
accidents among truck drivers. Occupational Medicine quarterly
journal 2011;3:14‑20.
20. Hosseinabadi R, Nowroozi K, Pooresmaile Z, Karimloo M,
Madah S. The effect of massage on acupoints to sleep quality in
elderly. Q J Rehabil 2008;9:8‑14.
21. Soleimany M, Nasiri Ziba F, Kermani A, Hosseini F. Comparison
of sleep quality in two groups of nurses with and without rotation
work shift hours. Indian J Nephrol 2007;20:29‑38.
22. Modarres M, Mirmohhamad Ali M, Oshrieh Z, Mehran A.
Comparison of the effect of mefenamic acid and Matricaria
camomilla capsules on primary dysmenorrhea. J Babol Univ Med
Sci 2011;13:50‑8.
23. Zick SM, Wright BD, Sen A, Arnedt JT. Preliminary examination
of the efficacy and safety of a standardized chamomile extract
for chronic primary insomnia: A randomized placebo‑controlled
pilot study. BMC Complement Altern Med 2011;11:78.
24. Cho MY, Min ES, Hur MH, Lee MS. Effects of aromatherapy
on the anxiety, vital signs, and sleep quality of percutaneous
coronary intervention patients in intensive care units. Evid Based
Complement Alternat Med 2013;2013:381381.
25. Sheikhi L, Karami B, Chopani J, Hokari S, Falah B. Evaluation
the status of sleep quality in elderly people in Kermanshah city.
J Rehabil Med 2015;3:81‑8.
26. Ahmadvand A, Sepehrmanesh Z, Ghoreishi F, Mousavi S.
Prevalence of insomnia among 18 years old people and over in
Kashan City, Iran in 2008. KAUMS J (FEYZ) 2010;13:313‑20.
27. Amsterdam JD, Shults J, Soeller I, Mao JJ, Rockwell K,
Newberg AB. Chamomile (Matricaria recutita) may provide
antidepressant activity in anxious, depressed humans: An
exploratory study. Altern Ther Health Med 2012;18:44‑9.
28. Amsterdam JD, Li Y, Soeller I, Rockwell K, Mao JJ, Shults J.
A randomized, double‑blind, placebo‑controlled trial of oral
Matricaria recutita (Chamomile) extract therapy for generalized
anxiety disorder. J Clin Psychopharmacol 2009;29:378‑82.
29. Moradi M, Mehrdad N, Nikpour S, Haghani H, Sharifi F. Heart
failure is one of the most common cardiovascular disorders.
In this disease heart is disable to perfusion. Inst J Nat Resour
2013;8:18‑25.
30. Langhorst J, Varnhagen I, Schneider SB, Albrecht U, Rueffer A,
Stange R, et al. Randomised clinical trial: A herbal preparation of
myrrh, chamomile and coffee charcoal compared with mesalazine
in maintaining remission in ulcerative colitis – A double‑blind,
double‑dummy study. Aliment Pharmacol Ther 2013;38:490‑500.
31. Montgomery P, Dennis J. A systematic review of
non‑pharmacological therapies for sleep problems in later life.
Sleep Med Rev 2004;8:47‑62.
32. Dadashpor A, Mohamadi R, Dadashpor A. Investigating effect of
a period of water exercise on sleep quality in male elders. J Shahid
Sadoughi Univ Med Sci 2013;21:300‑10.
33. Yazdani M, Shahriari M, Hamidi B. Comparison of fennel and
chamomile extract and placebo in treatment of premenstrual
syndromes and dysmenorrheal. Hamdan Med J 2004;8:57‑61.
34. Jenabi E, Ebrahimzadeh S. The effect of Matricaria chamomilla tea
on primary dysmenorrheal. J Med Plants 2009;8:39‑42.
35. Modares M, Besharat S, Rahimi Kian F, Besharat S, Mahmoudi M,
Salehi Sourmaghi H. Effect of ginger and chamomile capsules
on nausea and vomiting in pregnancy. J Gorgan Univ Med Sci
2012;14:46‑51. Available from: http://www.goums.ac.ir/journal/
browse.php?. [Last accessed 2017 Feb 06].
36. Karimian Z, Sadat Z, Abedzadeh M, Sarafraz N, Kafaei Atrian M,
Bahrami N. Comparison the effect of mefenamic acid and
Matricaria chamomilla on primary dysmenorrhea in Kashan
Medical University Students. Journal of Ardabil University of
Medical Sciences 2013;13:413‑20.
37. Shinomiya K, Inoue T, UtsuY, Tokunaga S, Masuoka T, Ohmori A,
et al. Hypnotic activities of chamomile and passiflora extracts in
sleep‑disturbed rats. Biol Pharm Bull 2005;28:808‑10.
38. Srivastava JK, Shankar E, Gupta S. Chamomile: A herbal medicine
of the past with bright future. Mol Med Rep 2010;3:895‑901.