. Mehdi Tazhibi; . Mohsen Dehghani; . Shadi Babazadeh; . Fariborz Makkarian; . Maryam Tabatabaeian; . Masoumeh Sadeghi; . Parisa Rezaei; . Mehri Faghihi
Volume 4, Issue 3 , June 2014, , Pages 1-5
Abstract
Background: Breast cancer is the most prevalent type of cancer among Iranian females;it is noteworthy that the condition of this type of cancer among Iranian women does notsignificantly ...
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Background: Breast cancer is the most prevalent type of cancer among Iranian females;it is noteworthy that the condition of this type of cancer among Iranian women does notsignificantly differ from what has been reported from other countries. Considering theimportance of this issue, identification of the backgrounds factors and risk factors of thebreast cancer risk are highly needed. Therefore, the present study is aimed to comparethe risk factors of resident patients of Isfahan province, Iran, with accredited risk factors byother countries and also identify the importance of each factor in the incidence of cancer.Materials and Methods: The present work is a case-control study, which was conductedin 2011. In order to conduct the study, 216 women who had been clinically identified withbreast cancer were selected from Seiedo-Shohada Hospital, Isfahan, Iran, as the case group.Moreover, 41 healthy women who were the relatives of the selected patients (i.e., sisters andaunts) were selected as the control group. The data and information of the patients from1999 to 2010 were collected from either assessing the database system of the center for breastcancer research or interviewing the patients through phone. To analyze the data, multiplelogistic regression method was applied. Results: The range of age among selected individualsin this study was from 20-75 years old. The determinant factors for odds of breast cancerincluded in the applied multiple logistic regression model were the use of oral contraceptivepills (OCPs) (odds ratio [OR] =0.18, 95% confidence interval [CI] = 0.04-0.75) as the protectivefactor, hormone replacement therapy (OR = 10.2, 95% CI = 1.18-88.89) and menopause atold age (OR = 1.26, 95% CI = 1.11-2.12) as the risk factors. Furthermore, there was not seenany significant relationship between age, vocation, and marital status with odds of breastcancer in multiple model. Conclusion: Basedon the results, use of OCPs as protectivefactor, hormone replacement therapy, andmenopause at old age are identified as therisk factors in developing breast canceramong women. Influencing and modifiablefactors should be considered very importantin society based interventions and preventiveinterventions planning.