. Jayesh Dalpatbhai Solanki; . Ajay P. Kapadiya; . Hemant B. Mehta; . Chinmay J. Shah
Volume 9, Issue 4 , April 2019, , Pages 1-5
Abstract
BACKGROUND: Sympathetic overactivity mediates abnormal cardiovascular outcome that is affectedby stress, lack of physical activity (PA), and familial hypertension (HTN). It can be assessed ...
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BACKGROUND: Sympathetic overactivity mediates abnormal cardiovascular outcome that is affectedby stress, lack of physical activity (PA), and familial hypertension (HTN). It can be assessed by bloodpressure‑based sympathetic function tests.OBJECTIVE: We studied sympathetic function tests in young nonathletic males in relation to measuresof obesity, PA, and familial HTN.METHODOLOGY: We recruited 100 males (mean age: 19 years) and measured body massindex (BMI) and body composition parameters by tetrapolar bioelectrical impedance such as total bodyfat, visceral fat, subcutaneous fat, and skeletal muscle mass. Using instrument cardiac autonomicneuropathy system of Recorders and Medicare System Company, India, blood pressures (supine,standing, and post hand grip) were recorded and studied quantitatively and qualitatively.RESULTS: Physically active and inactive individuals (n = 50 each) had comparable age, BMI,measures of obesity, and sympathetic function tests. However, individuals with familial HTN (n = 37)showed significantly higher obesity measures and blood pressures (supine: systolic bloodpressure [SBP] – 133 vs. 115 and diastolic blood pressure [DBP] – 79 vs. 76; standing: SBP – 136 vs.122 and DBP – 80 vs. 76; post hand grip: SBP – 136 vs. 125 and DBP – 86 vs. 81). Qualitatively,postural hypotension was seen in only two individuals, while worst grading was in post hand griptest significantly and more so in physically inactive group (30%, 28%, and 42% vs. 16%, 20%, and64%) and individuals with positive familial HTN (32%, 38%, and 30% vs. 17%, 13%, and 70%).CONCLUSION: Familial HTN, but not physical inactivity, affects sympathetic functioning in nonathleticyoung male medical personnel. It asks for other lifestyle modifications for better cardiovascular healthas primary prevention.