. Maryam Sadat Hosseini; . Afsaneh Hosseini; . Elnaz Ghaffari; . Mitra Radfar; . Fariba Shirvani; . Shahrzad Tabatabai; . Dariush Abtahi; . Mahsa Mirhadi; . Maziyar Mortazavi; . Shideh Ariana
Volume 11, Issue 4 , May 2021, , Pages 1-9
Abstract
BACKGROUND: The coronavirus, which is caused by acute respiratory syndrome, appeared inWuhan, China, in December 2019 and gradually spread around the world until almost all countriesbecame ...
Read More
BACKGROUND: The coronavirus, which is caused by acute respiratory syndrome, appeared inWuhan, China, in December 2019 and gradually spread around the world until almost all countriesbecame infected with the coronavirus. In Iran, the outbreak of coronavirus began on February 21,2020, with the report of infection of two people in the city of Qom. The aim of this study is to evaluatethe clinical findings of neonates born to pregnant women with corona disease.MATERIALS AND METHODS: During this case study (February 21 to November 30, 2020), out of88 pregnant mothers who referred to the hospitals of Shahid Beheshti University of Medical Sciences,44 live neonates were born from 42 pregnant women with COVID‑19, who were evaluated for clinicalsigns by studying their files and reported as a case series, due to limited samples, No statisticalanalysis of the study was performed.RESULTS: In studies of clinical records of hospitalized mothers and infants, among the polymerasechain reactions (PCRs) provided for all infants, one PCR was reported positive 2 days after birth,whereas this infant 10 min after birth, immediately after routine procedures, due to positive mother’sPCR was isolated from the operating room. However, all of the infant’s clinical symptoms were normalduring the 3‑day hospital stay for routine postpartum care. Twenty‑eight days after birth, the babywas reevaluated for clinical, laboratory, and chest X‑ray symptoms, all of which were normal. ThePCR of other neonates was negative, and five intubated neonates, two twin, and two single died, andthe other neonates were discharged. In evaluating the clinical records of mothers of these infants,the mean age is 30 years, and the average gestational age is 35 weeks, 32 cases of caesareansection, and 10 cases of normal delivery.CONCLUSION: We describe epidemiological data, demographics, signs and symptoms onadmission, laboratory results, comorbidities, infection COVID‑19 in the mothers and neonates,chest radiography and computed tomography findings, treatment received for COVID‑19, andclinical maternal, fetal, and neonatal outcomes. Due to the fact that the study population issmall consist of 42 mothers with COVID‑19 infection, among all PCR samples from infantsborn to COVID‑19 positive mothers, the PCR result of one case was positive, and the rest ofwas negative. Therefore, vertical transmission of COVID‑19 through the placenta to the fetuscannot be confirmed or denied, nor can the COVID‑19 confirmed or denied the baby’s postnatalcomplication during pregnancy.