Journal of Education and Health Promotion

Application of joinpoint regression in determining breast cancer incidence rate change points by age and tumor characteristics in women aged 30–69 (years) and in Isfahan city from 2001 to 2010

. Zahra Fazeli Dehkordi; . Mehdi Tazhibi; . Shadi Babazade

Volume 4, Issue 5 , November 2014, , Pages 1-10

Abstract

Background and Objectives: Breast cancer is a major threat to women’s health. Evaluationof the changes in trend of the incidence rate provides valuable information for the assessmentand ... Read More

Hormonal and reproductive risk factors associated with breast cancer in Isfahan patients

. Mehdi Tazhibi; . Mohsen Dehghani; . Shadi Babazadeh; . Fariborz Makkarian; . Maryam Tabatabaeian; . Masoumeh Sadeghi; . Parisa Rezaei; . Mehri Faghihi

Volume 4, Issue 3 , June 2014, , Pages 1-5

Abstract

Background: Breast cancer is the most prevalent type of cancer among Iranian females;it is noteworthy that the condition of this type of cancer among Iranian women does notsignificantly ... Read More Background: Breast cancer is the most prevalent type of cancer among Iranian females;it is noteworthy that the condition of this type of cancer among Iranian women does notsignificantly differ from what has been reported from other countries. Considering theimportance of this issue, identification of the backgrounds factors and risk factors of thebreast cancer risk are highly needed. Therefore, the present study is aimed to comparethe risk factors of resident patients of Isfahan province, Iran, with accredited risk factors byother countries and also identify the importance of each factor in the incidence of cancer.Materials and Methods: The present work is a case-control study, which was conductedin 2011. In order to conduct the study, 216 women who had been clinically identified withbreast cancer were selected from Seiedo-Shohada Hospital, Isfahan, Iran, as the case group.Moreover, 41 healthy women who were the relatives of the selected patients (i.e., sisters andaunts) were selected as the control group. The data and information of the patients from1999 to 2010 were collected from either assessing the database system of the center for breastcancer research or interviewing the patients through phone. To analyze the data, multiplelogistic regression method was applied. Results: The range of age among selected individualsin this study was from 20-75 years old. The determinant factors for odds of breast cancerincluded in the applied multiple logistic regression model were the use of oral contraceptivepills (OCPs) (odds ratio [OR] =0.18, 95% confidence interval [CI] = 0.04-0.75) as the protectivefactor, hormone replacement therapy (OR = 10.2, 95% CI = 1.18-88.89) and menopause atold age (OR = 1.26, 95% CI = 1.11-2.12) as the risk factors. Furthermore, there was not seenany significant relationship between age, vocation, and marital status with odds of breastcancer in multiple model. Conclusion: Basedon the results, use of OCPs as protectivefactor, hormone replacement therapy, andmenopause at old age are identified as therisk factors in developing breast canceramong women. Influencing and modifiablefactors should be considered very importantin society based interventions and preventiveinterventions planning.

The efficacy of hepatitis B vaccine in Iranian population: A systematic review and meta‑analysis

. Mehdi Tazhibi; . Abdollah Hajivandi; . Arefeh Dehghani Tafti; . Hossein Fallahzadeh

Volume 4, Issue 3 , June 2014, , Pages 1-8

Abstract

Introduction: Hepatitis B infection is an important health problem all over the world, andaccording to the studies, Iran is a country with intermediate prevalence, so vaccination is ... Read More

Investigation of the age trends in patients with breast cancer and different sizes of tumors in Breast Cancer Research Center of Isfahan University of Medical Sciences in 2001‑2010

. Mehdi Tazhibi; . Zahra Fazeli Dehkordi; . Shadi Babazadeh; . Maryam Tabatabaeian; . Parisa Rezaei; . Mehri Faghihi

Volume 4, Issue 2 , May 2014, , Pages 1-4

Abstract

Background: Breast cancer is the most common cause of death in women in the age rangeof 35‑55 years. Each year, one or two cases of breast cancer per 1000 women are diagnosedas new ... Read More Background: Breast cancer is the most common cause of death in women in the age rangeof 35‑55 years. Each year, one or two cases of breast cancer per 1000 women are diagnosedas new cases. Despite the serious prognosis and high rate of morbidity, mortality, andpathogenicity, in the case of early diagnoses, the prognosis will be better. The aim of thisstudy was to investigate the age trends in breast cancer patients with different sizes of tumorsin Breast Cancer Research Center of Isfahan University of Medical Sciences in 2001‑2010.Materials and Methods: The information in radiotherapy and oncology of Isfahan University ofMedical Sciences and Milad Hospital from 2001 to 2010 were coded and analyzed. Frequencyof patients’ age groups, tumor sizes and the year of cancer diagnosis were calculated.Correlation test was used for data analysis in statistical analysis in social science (SPSS)software version 18. Findings: Among the 3722 patients with breast cancer, the highestrelative frequency distribution, respectively was observed in the age of 40‑49 years (34.4%),50‑59 years (26.6%), 30‑39 years (17.7%), 60‑69 years (13.2%), 20‑29 years (2.5%), 70 yearsand older (5.2%) and less than 20 years. Relative frequency distribution of tumor sizes in avariety of 5 cm (T2) was with the frequency of 59.8%, and then 26% at 5 cm (T3), 10.5% at2 cm (T1), 3.1% at T4 and 0.6 at In‑situ, respectively. Conclusion: The investigation of agetrends showed that diagnosis rate of breast cancer increased from 2001 to 2004. It reached itshighest value in 2006 at the age range of 30‑39 years. Then, the trend has been downward, andit has continued to decline until 2010, whichcould be the result of the equipping screeningsystem and recording the malignant cases.85.8% of the examined tumors in T2 and T3group were visible and may be disturbing.Comparing the frequency distribution of theinfected population showed that the highestincidence of breast cancer diagnosis were inthe age range of 40‑49 years. It seems that aslong as the mass has not reached an obviouspalpable state, it has not been diagnosed.

Comparison of satisfactions from mastectomy and Lump Ectome in breast cancer patients

. Mehdi Tazhibi; . heida Sarrafzadeh; . Fariborz Mokarian; . Shady Babazade; . Maryam Tabatabaeian; . Parisa Rezaei; . Mehri Faghihi; . Fariba Taleghani

Volume 4, Issue 1 , February 2014, , Pages 1-4

Abstract

Introduction: The prevalence of breast cancer among women in compare to other types ofcancers in all over the world and in Iran is high. Mastectomy surgery is one of the commontreatments ... Read More

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Author = . Mehdi Tazhibi

Application of joinpoint regression in determining breast cancer incidence rate change points by age and tumor characteristics in women aged 30–69 (years) and in Isfahan city from 2001 to 2010

Abstract

Hormonal and reproductive risk factors associated with breast cancer in Isfahan patients

Abstract

The efficacy of hepatitis B vaccine in Iranian population: A systematic review and meta‑analysis

Abstract

Investigation of the age trends in patients with breast cancer and different sizes of tumors in Breast Cancer Research Center of Isfahan University of Medical Sciences in 2001‑2010

Abstract

Comparison of satisfactions from mastectomy and Lump Ectome in breast cancer patients

Abstract