. Vahid Falahati; . Ali Ghasemi; . Kazem Ghaffari; . Aziz Eghbali; . Sanaz Khodabakhshi; . Amir Almasi‑Hashiani; . Bahman Sadeghi‑Sedeh; . Mostafa Shanbehzadeh
Volume 12, Issue 10 , November 2022, , Pages 1-7
Abstract
BACKGROUND: Iron deficiency anemia (IDA) is one of the most common anemias, especially inchildren 4–23 months. Therefore, prophylaxis is necessary to improve iron status as well ...
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BACKGROUND: Iron deficiency anemia (IDA) is one of the most common anemias, especially inchildren 4–23 months. Therefore, prophylaxis is necessary to improve iron status as well as reduceIDA in Toddlers. The aim of this study was to compare the efficacy of daily supplementation withferrous gluconate (FG) and ferrous sulfate (FS) on iron status in toddlers.MATERIALS AND METHODS: A total of 120 healthy toddlers were divided randomly into 2 groups atthe Amir‑Kabir Hospital, Arak, Iran and received FS and FG from March 2020 to December 2020. Ironstatus was evaluated at baseline and after 6 months of supplementation. The statistical significanceof the differences in iron status between FS and FG groups was calculated using Student’s t‑testand the Pearson’ s Chi‑square test for qualitative variables. SPSS software (version 16, Chicago,IL, USA) was used for statistical analysis.RESULTS: Comparison of iron status of FS and FG groups toddlers at baseline and after 6 monthsof supplementation showed that there was a significant difference in hemoglobin (Hb) (10.46 vs.12.45, P = 0.001) and ferritin level (28.08 vs. 59.63, P = 0.001).CONCLUSIONS: Although prophylaxis with FG led to a higher Hb and ferritin levels, our studyrecommended that both FG and FS supplements were effective for prophylactic use in theprevention of IDA. However, FG was more effective than FS because FG group that received FGsupplementation indicated a higher Hb and ferritin levels in comparison to the FS group that receivedFS supplementation.